Store leftover Zucchini Roll-Ups in an airtight container in the refrigerator for up to 4 days. Do not freeze this dish because the thawed squash becomes mushy and releases excess water into the cheese. Reheat portions in a preheated 350°F oven for 12 to 15 minutes until hot. You can also microwave on high for 90 seconds, though the oven keeps the cheese top crispier.